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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Bacteriocin IId ： ウィキペディア英語版 Bacteriocin IId Bacteriocin AS-48 is a cyclic peptide antibiotic produced by the eubacteria ''Enterococcus faecalis'' (Streptococcus faecalis) that shows a broad antimicrobial spectrum against both Gram-positive and Gram-negative bacteria. Bacteriocin AS-48 is encoded by the pheromone-responsive plasmid pMB2, and acts on the plasma membrane in which it opens pores leading to ion leakage and cell death. The globular structure of bacteriocin AS-48 is composed of five alpha helices enclosing a hydrophobic core. The mammalian NK-lysin effector protein of T and natural killer cells has a similar structure, though it lacks sequence homology with bacteriocins AS-48. Bacteriocin uses components of the mannose phosphotransferase system (man-PTS) of susceptible cells as target/receptor. The immmunity protein LciA forms a strong complex with the receptor proteins and the bacteriocin, thereby preventing cells from being killed. The complex between LciA and the man-PTS components (IIAB, IIC, and IID) appears to involve an on–off type mechanism that allows complex formation only in the presence of bacteriocin; otherwise no complexes were observed between LciA and the receptor proteins.〔 〕 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bacteriocin IId」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.